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Clorhexadine and fibroblast inhibition

I have been recently told at a dental convention that the use of chlorhexdine is not recommended after periodontal therapy as studies have shown that it inhibits fibroblasts and healing? Any thoughts or case studies that prove this?



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1 Answer

Research has shown that chlorhexadine is the gold standard as far as an antimicrobial agent, however research has also show it does inhibit fibroblast attachment. Here are some links to research:
 
http://www.sciencedirect.com/science/article/pii/S0887233307002536
http://www.scielo.br/scielo.php?pid=S1678-77572010000100010&script=sci_arttext&tlng=e!n
http://www.ncbi.nlm.nih.gov/pubmed/10632519
http://www.ncbi.nlm.nih.gov/pubmed/1625152
http://www.ncbi.nlm.nih.gov/pubmed/1920010
http://www.ijdr.in/article.asp?issn=0970-9290;year=2008;volume=19;issue=1;spage=29;epage=35;aulast=Flemingson

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